»
Antibodies
»
anti-Pyrraline antibody (Peroxidase)
Pyrraline antibody (Peroxidase)
| Antigen |
|
| Clonality |
Monoclonal (H12) |
|
Host
|
|
|
Reactivity
|
|
|
Conjugate
|
|
|
Application
|
|
| Catalog no. |
ABIN289942 |
| Quantity |
20 ug (0.25 mg/ml) |
| Price |
1,142.89 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Immunogen
|
Pyrraline-HSA
|
|
Format
|
Affinity-purified
|
|
Isotype
|
IgG1
|
|
Clone
|
H12
|
|
Description
|
Reaction of protein amino groups with glucose leads, through the early products such as a Schiff base andAmadori rearrangement products, to the formation of advanced glycation end products (AGEs). Recentimmunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modified proteinsin several human tissues: human lens (nondiabetic and noncataractous), renal proximal tubules inpatients with diabetic nephropathy and chronic renal failure, diabetic retina, peripheral nerves ofdiabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulin forming amyloid fibrilsin patients with hemodialysis-related amyloidosis, senile plaques of patients with Alzheimer
|
|
Application Notes
|
Working dilution for immunohistochemistry: about 2ug/ml, for ELISA: 0.1-0.5ug/ml
|
|
Concentration
|
0.25 mg/ml
|
|
Purification
|
The splenic lymphocytes from BALB/c mouse, immunized with pyrraline-HSA were fused to myeloma P3U1 cells. The cell line (H12) with positive reaction was grown in ascitic fluid of BALB/c mouse, from which the antibody was purified by Protein Gaffinity chromatography and conjugated.
|
|
Buffer
|
PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
|
|
Storage
|
Store below -20
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Pyrraline", type "Antibodies"
Alternatives 
