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Antibodies
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anti-Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member ...
Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11) antibody
| Antigen |
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| Synonyms |
xCT, CCBR1, sut, AI451155, 9930009M05Rik, SLC7A11, DKFZp468E122 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
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| Catalog no. |
ABIN289953 |
| Quantity |
25 ug (0.1 mg/ml) |
| Price |
865.64 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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Cystine / Glutamic Acid Transporter (xCT)
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Immunogen
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Partial peptide of Mouse Cystine / Glutamic Acid Transporter (xCT)
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Format
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Affinity-purified
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Description
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Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection ofamino acid molecule variety, and is classfied into various transport systems by the transportative substrateselectivity and the Na+ dependence with the reflection of amino acid molecule variety.The amino acid transporter, cystine/glutamic acid transporter (xCT) for system xchas been proposed to beresponsible for the cystine transport through the plasma membrane. System xc mediates an amino acid exchange and prefers cystine and glutamate as its substrates. The transporter designated as xCT requires 4F2 heavy chain (4F2hc:CD98) for its functional expression, and belongs to the family of amino acidtransporters which associates with the type II membrane glycoproteins such as 4F2hc. In brain, it has beenproposed that system xcis up-regulated in glial cells upon the oxidative stress and plays an essential rolesto protect neurons against oxidative stress. This antibody has been proved to be useful for immunoblotting and immunohistochemistry. Considering the peptide amino acid sequence, this antibody also seems to react with human xCT.
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Application Notes
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Working dilution for Immunohistochemistry: 5ug/ml ,for immunoblotting: 1ug/ml
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Concentration
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0.1 mg/ml
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Purification
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This antibody was purified from rabbit serum immunized with synthesized peptideof N- end of mouse xCT by peptide affinity chromatography.
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Buffer
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PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
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Storage
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Store below -20
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Restrictions
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For Research Use only
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Alternatives for antigen "Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11)", type "Antibodies"
