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CML antibody

Antigen

CML

Clonality Monoclonal (NF-1G)
Host
Alternatives

Mouse

Reactivity
Alternatives

All Species

Application
Alternatives Immunohistochemistry (IHC), ELISA
Catalog no. ABIN289956
Quantity 50 ug  (0.25 mg/ml)
Price 942.65 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Immunogen CML-HSA
Format Affinity-purified
Isotype IgG2a  (Matching secondary antibodies)
Clone NF-1G
Description Reaction of protein amino groups with glucose leads, through the early products such as a Schiff base andAmadori rearrangement products, to the formation of advanced glycation end products (AGEs). Recentimmunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modified proteinsin several human tissues: human lens (nondiabetic and noncataractous), renal proximal tubules inpatients with diabetic nephropathy and chronic renal failure, diabetic retina, peripheral nerves ofdiabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulin forming amyloid fibrilsin patients with hemodialysis-related amyloidosis, senile plaques of patients with Alzheimer

Application Details

Application Notes Working dilution for immunohistochemistry: 5-10ug/ml, for ELISA: 0.1-1.0ug/ml
Concentration 0.25 mg/ml
Purification The splenic lymphocytes from BALB/c mouse, immunized with CML-HSA were fused tomyeloma P3U1 cells. The cell line (NF-1G) with positive reaction was grown in ascitic fluid ofBALB/c mouse, from which the antibody was purified by Protein G affinity chromatography.
Buffer PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
Storage Store below -20
Restrictions For Research Use only

Alternatives

Alternatives for antigen "CML", type "Antibodies"
Hosts Mouse (8)
Reactivities All Species (5)
Applications Immunohistochemistry (IHC) (5), ELISA (3), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2)
Conjugates Biotin (2), Peroxidase (POD) (2)