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Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 7 (Slc7a7) antibody

Antigen

Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 7 (Slc7a7)

Synonyms TA1, 4F2LC, D0H16S474E, SLC7A5, JHI-21, LAT1, my+lat1, AI790233, y+LAT1, MGC78892, MGC123300, zgc:123300
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Immunohistochemistry (IHC)
Catalog no. ABIN289962
Quantity 25 ug  (0.1 mg/ml)
Price 865.64 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name L-type Amino Acid Transporter 1(LAT1)
Immunogen Partial peptide of Human L-type Amino Acid Transporter 1(LAT1)
Format Affinity-purified
Description Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection ofamino acid molecule variety, and is classfied into various transport systems by the transportative substrateselectivity and the Na+ dependence with the reflection of amino acid molecule variety.L-type amino acid transporter 1 (LAT1) is a predicted 12 membrane-spanning protein and is uniquebecause it requires an additional single membrane spanning protein, 4F2 heavy chain (4F2hc:CD98), for itsfunctional expression. L-type is Na+ -independent neutral amino acid transporter agency and essential forthe transporter of large neutral amino acid such as Leucine, Isoleucine, Varine through the plasmamembrane. LAT1 is, thus transporter responsible for the permeation of aromatic or branched-chain aminoacids and amino acid-related drugs such as L-DOPA. LAT has been proposed to be one of the majornutrient transport systems at the blood-brain barrier. Highly regulated nature and high level of expression intumor cell lines, LAT is thought to be up-regulated to support the high protein synthesis for cell glowth andcell activation.This antibody has been proved to be useful for the immunohistochemistry.

Application Details

Application Notes Working dilution for immunohistochemistry: 5-10ug/ml
Concentration 0.1 mg/ml
Purification This antidody was purified from rabbit serum immunized with synthesized peptide ofC- end of human LAT1 and has been proved to be useful for the immunohistochemistry
Buffer PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
Storage Store below -20
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 7 (Slc7a7)", type "Antibodies"
Hosts Mouse (1)
Reactivities Human (1)
Applications Immunohistochemistry (IHC) (1)