SLC22A7 antibody

Catalog No. ABIN289967

Product Details anti-SLC22A7 Antibody

Target: SLC22A7 (Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A7 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT2 by peptide affinity chromatography.

Immunogen: Partial peptide of Human Organic Anion Transporter 2 (OAT2)

Application Details

Application Notes: Working dilution for immunohistochemistry 5ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for SLC22A7

Target: SLC22A7 (Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7))

Alternative Name: Organic Anion Transporter 2 (OAT2) (SLC22A7 Products)

Synonyms: NLT antibody, OAT2 antibody, Oat2 antibody, oat2 antibody, nlt antibody, slc22a7 antibody, im:6901703 antibody, im:7155670 antibody, oat2a antibody, zgc:162334 antibody, oat2e antibody, slc22a7b antibody, zgc:63958 antibody, solute carrier family 22 member 7 antibody, solute carrier family 22 (organic anion transporter), member 7 antibody, solute carrier family 22 (organic anion transporter), member 7 L homeolog antibody, solute carrier family 22 (organic anion transporter), member 7a antibody, solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1 antibody, SLC22A7 antibody, Slc22a7 antibody, slc22a7.L antibody, slc22a7a antibody, slc22a7b.1 antibody

Background: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Organic anion transporter 2 (OAT2) is predicted 12 putative membrane-spanning protein, and which is expressed predominantly in the liver and only weakly in the kidney. OAT2 mediates the Na+-independent transport of organic anions, such as salicylate, and also mediates the transport of prostaglandin E2 (PGE2),methotrexate, acetylsalicylate and PAH (p-aminohippurate).This has been proved to be useful for immunohistochemistry .