Add to Basket
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

PEDF antibody

Antigen

PEDF

Clonality Monoclonal (14K)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Western Blotting (WB)
Catalog no. ABIN289972
Quantity 50 ug  (0.25 mg/ml)
Price 942.65 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information

Immunogen Partial peptide of Human PEDF-KLH
Format Affinity-purified
Isotype IgG1  (Matching secondary antibodies)
Clone 14K
Description Pigment Epithelium-Derived Factor ( PEDF ), a protein previously shown to have neurotrophic activity,is indispensable for neuronal development, differentiation and existence adjacent to retina.The amount of inhibitory PEDF produced by retinal cells was positively correlated with oxygenconcentrations,suggesting that its loss play a permissive role in ischemia-driven retinal neovascularization.So that, PEDF is likely to contribute to regulate of blood vessels growth in eye by creating a permissiveenvironment for angiogenesis when oxygen is limiting and an inhibitory environment oxygenconcentrations are normal or high ( Science Vol 285: 245-248,1999).PEDF may be a therapeutic target pathologic ocular neovascularization as well as for retinoblastomas.This antibody could detect PEDF with western-blotting method in medium of retinal pigment epitheliumcell. This antibody is useful in research for angionenesis and neuronal system.

Application Details

Concentration 0.25 mg/ml
Purification The cell line was grown on serum free medium, from which the antibody was purified by Protein G affinity chromatography.
Buffer PBS (containing 0.1% BSA as a stabilizer, 0.1% Proclin as a bacteriostat)
Storage Store below -20
Restrictions For Research Use only

Alternatives

Alternatives for antigen "PEDF", type "Antibodies"
Hosts Mouse (4)
Reactivities Human (7)
Applications ELISA (7), Western Blotting (WB) (7)