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Organic Anion Transporter 1 (OAT1) antibody
| Antigen | Organic Anion Transporter 1 (OAT1) |
| Synonyms | OAT1, PAHT, HOAT1, ROAT1, FLJ55736, MGC45260 |
| Clonality | Polyclonal |
| Host |
Rabbit |
| Reactivity |
Human |
| Application |
Immunohistochemistry (IHC)
|
| Catalog no. | ABIN289973 |
| Quantity | 25 ug (0.1 mg/ml) |
| Price | 865.64 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | Organic Anion Transporter 1(OAT1) |
| Immunogen | Partial peptide of Human Organic Anion Transporter 1(OAT1) |
| Format | Affinity-purified |
| Description | To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for theelimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Human Organic anion transporter 1(OAT1) encodes a 563 amino acid residue protein, and which ispredicted 12 putative membrane-spanning protein. Human OAT1 was found to be expressed predominantlyin the kidney and only weakly in the brain. OAT1 mediates the Na+-independent transport of organic anions,such as PAH (p-aminohippurate), cyclic nucleotides, prostanoides, dicaroxylates, and many anion drugs.This antibody has been proved to be useful for immunohistochemistry . |
Application Details
| Application Notes | Working dilution for immunohistochemistry 5ug/ml |
| Concentration | 0.1 mg/ml |
| Purification | This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT1 by peptide affinity chromatography. |
| Buffer | PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat) |
| Storage | Store below -20 |
| Restrictions | For Research Use only |
