Galectin, Galactoside-Binding, Soluble, 3 (LGALS3) antibody

Antigen: Galectin, Galactoside-Binding, Soluble, 3 (LGALS3)

Synonyms: galectin-3, LGALS3, Galectin-3, MGC148757, leg3

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN289975

Additional Information

Alternative name: Galectin-3

Immunogen: polyclonal antibody raised against recombinant human galectin-3

Format: Affinity-purified

Description: The galectins are a family of carbohydrate-binding proteins that are distributed widely inmetazoan organisms. Many galectin family members are detected primarily intracellularly inmost of the systems studied, although certain members can be found both inside and outsideof cells. Galectin-3 interacts with beta-galactoside residues of several cell surface and matrixglycoproteins through the carbohydrate recognition domain and is also capable of peptide-peptide associations mediated by its N-terminus domain. Recently, it has beendemonstrated that galectin-3 is a new member of AGEs-receptor complex. (Mol.Med.1:634-646,1995). This antibody is affinity purified rabbit polyclonal antibody raised against recombinant human galectin-3 and should be used for western blotting.

Application Details

Concentration: 0.25 mg/ml

Purification: This antibody was purified from rabbit serum by Protein G affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Storage: Store below -20

Research Area: Neurology

Restrictions: For Research Use only

Images

Western blotting Sample: Cell lysates ofGelectin-3 CHO or mockCHO cells (10ug/lane). Preparation of antibodies and instruction: Prof. S Horiuch.,Department of Biochmistry Kumamoto UniversitySchool of Medicine. Zhu,W.et al.:Biochem Biophys Res Commun 280:11831188,(2001)