Jub, Ajuba Homolog (Xenopus Laevis) (JUB) antibody

Antigen: Jub, Ajuba Homolog (Xenopus Laevis) (JUB)

Synonyms: Ajuba, MGC15563, JUB, MGC93830, fj66b05, wu:fj66b05

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunocytochemistry (ICC), Immunoprecipitation (IP)

Catalog no.: ABIN290002

Additional Information

Alternative name: Ajuba

Immunogen: GST-Human Ajuba fusion Protein

Format: Affinity-purified

Description: Aurora-A(Aurora-A/STK-15/Aik) encoding a centrosome-associated Ser/Thr kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. In vitro transformation activityof Aurora-A suggested to be a potential oncogene. Recent research elucidated that Ajuba, Aurora-A bindingprotein, induces the autophosphorylation and consequent activation of Aurora-A . In the future thisantibody will contribute the research progress whether Ajuba and Aurora-A are involed in tumorigenesis.This antibody is useful for immunoprecipitation and immunocytochemistry.

Application Details

Application Notes: Working dilution For Immunoprecipitation , 10 ug/mlFor Immnocytochemistry , 2-5 ug/ml

Concentration: 0.25 mg/ml

Purification: This antibody was purified from rabbit serum by affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Storage: Store below -20

Restrictions: For Research Use only

Images

Immnocytochemistry Sample : HeLa CellPreparation of antibodies and instruction: Dr. Saya H. and Dr. Hirota T. at Department of Tumor Genetics and Biology, Kumamoto University School of medicine.