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Organic Cation Transporter 3 (OCT3) antibody

Antigen

Organic Cation Transporter 3 (OCT3)

Synonyms EMT, EMTH, OCT3, Oct3, Orct3, Slca22a3
Clonality Polyclonal
Host

Rabbit

Reactivity

Rat (Rattus)

Application
Immunohistochemistry (IHC)
Catalog no. ABIN290005
Quantity 25 ug  (0.25 mg/ml)
Price 865.64 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name Organic Cation Transporter 3
Immunogen Partial peptide of Rat Organic Cation Transporter 3
Format Affinity-purified
Description To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for theelimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fallinto various transport systems by the transportative substrate. In particular, oraganic ion transporter familyis comprised of organic anion transport family (OAT), oraganic cation transport family (OCT),OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates ofwhich include a lot of both endogeneous and exogeneous anions.Organic Cation Transporter 3 (OCT3) is expressed in kidney, placenta and brain. In brain, OCT3 issuggested that it is involved in monoamine regulation mechanism and plays a significant role in the disposition of cationic neurotoxins.This antibody was established from the purified serum immunized with partial peptide of rat OCT3. This antibody is useful for Immnohistochemistry.

Application Details

Application Notes Working dilution For Immunohistochemistry , 1-5 ug/ml
Concentration 0.25 mg/ml
Purification This antibody was purified from rabbit serum by affinity chromatography.
Buffer PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
Storage Store below -20
Restrictions For Research Use only