Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) antibody

Antigen: Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1)

Synonyms: VR1, DKFZp434K0220, Vr1, Vr1l1, VR.5'sv, VR-1, OTRPC1, TRPV1beta, TRPV1alpha, TRPV1, Trpv1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN290043

Additional Information

Alternative name: phospho TRPV1 (VR-1)

Immunogen: Partial peptide of Rat Phospholipid scramblase 2

Format: Affinity-purified

Description: Recent work has begun to clarify the function of ionotropic receptors, which are expressed in sensory neurons and promote nociception. The most representative receptors of this class belong to TRP ion channel superfamilycomprised by seven sub-families, TRPC, TRPV, TRPP, TRPM, TRPN, TRPML and TRPA.TRPVl channels have six transmembrane domains that most probably assemble into tetramers to formnon-selective cationic channels. The first cloned TRPV receptor was TRPV1. This receptor is activated by capsaicin, protons or heat (with a threshold > ~43

Application Details

Application Notes: Working dilution For Western blotting 0.5ug/ml

Concentration: 0.25 mg/ml

Purification: This antibody was established from the serum of a rabbit immunized with the partial peptide representing phosphorylated TRPV1 at S800, and purified by peptide affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Storage: Store below -20

Restrictions: For Research Use only

Images

Western blotting Sample: phosphorylated TRPV1 at S800 in HEK293 cells. Preparation of antibodies and instruction: Dr. Makoto Tominaga at Section of Cell Signaling,Okazaki Institute for Integrative Bioscience,National Institutes of Natural Sciences