Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibody

Antigen: Peroxisome Proliferator-Activated Receptor gamma (PPARG)

Synonyms: MGC139055, PPARG, GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, Nr1c3, PPAR-gamma, PPARgamma2, PPAR-gamma2, PPARGAMMA

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN290044

Additional Information

Alternative name: PPARgamma

Immunogen: Partial peptide of Human PPAR gamma

Format: Affinity-purified

Description: PPARs (peroxisome proliferator-activated receptors) are a family of transcription factors belonging tothe nuclear hormone receptor superfamily. Widely expressed in vertebrates, PPARs play critical roles inmetabolism and differentiation of a number of cell types.The PPAR gamma subtype was originally identified as a factor binding to a fatty acid specific enhancer of the aP2 gene. PPAR-gamma actions are mediated by three isoforms resulting from alternative promoter selection andalternative splicing. PPAR-gamma1 is widely expressed while PPAR-gamma2 expression is restricted to adipose tissueand PPAR-gamma3 expression is restricted to adipose tissue, macrophage, and colon.PPAR gamma participates in adipose cell differentiation and energy storage (Ref.1).Recently, these roles of PPARgamma have focused attention on PPARgamma as a target of the anti-diabeticthiazolidinedione class of drugs (Ref.2).

Application Details

Application Notes: Working dilution For Western blotting: 1.0ug/ml

Concentration: 0.25 mg/ml

Purification: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the C-terminal domain of Human PPARgamma, and purified by peptide affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Storage: Store below -20

Restrictions: For Research Use only

Images

Western blotting Sample: Extracted proteins from mouse adipose tissue