Adiponectin Receptor 1 (ADIPOR1) antibody

Antigen: Adiponectin Receptor 1 (ADIPOR1)

Synonyms: ADIPOR1, adipor1, zgc:92893, CGI45, PAQR1, ACDCR1, CGI-45, TESBP1A, FLJ25385, FLJ42464, Paqr1, 2810031L11Rik, zgc:55386, wu:fj02d08, MGC127115, cgi45, paqr1, acdcr1, cgi-45, tesbp1a, MGC79827, MGC53458, MGC114758, Adipor1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN290045

Additional Information

Alternative name: AdipoR1

Immunogen: Partial peptide of Human AdipoR1

Format: Affinity-purified

Description: Obesity is a common etiology of diabetes mellitus and other diseases. Certain adipocytokines areconsidered beneficial due to their ability to enhance insulin sensitivity, while others, considereddetrimental, enhance insulin resistance.The beneficial adipocytokine adiponectin displays both anti-diabetic and anti-arteriosclerotic effects. Two distinct adiponectin receptors have been identified. Both AdipoR1 and AdipoR2 are seven-passtransmembrane receptors but are structurally, topologically, and functionally distinct from G-proteincoupled receptors (GPCR) (Ref.1). AdipoR1 is most abundant in muscle whereas AdipoR2 is mostabundant in liver. Both receptors promote fatty acid oxidation and glucose uptake by AMP-activatedprotein kinase and PPAR gamma.PPAR agonists are reported to increase expression of activated adiponectin. PPAR gamma agonists also increase expression of adiponectin receptors (Ref.2). Such findings have focused attention on the role of AdipoR1 in PPAR agonist development.

Synonyms: ADIPOR1, adipor1, zgc:92893, CGI45, PAQR1, ACDCR1, CGI-45, TESBP1A, FLJ25385, FLJ42464, Paqr1, 2810031L11Rik, zgc:55386, wu:fj02d08, MGC127115, cgi45, paqr1, acdcr1, cgi-45, tesbp1a, MGC79827, MGC53458, MGC114758, Adipor1

Application Details

Application Notes: Working dilution For Western blotting: 1.0ug/ml

Concentration: 0.25 mg/ml

Purification: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the N-terminal domain of Human AdipoR1, and purified bypeptide affinity chromatography.

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Storage: Store below -20

Restrictions: For Research Use only

Images

Western blotting Sample: (1) Extracted proteins from mouse muscle (2) Extracted proteins from mouse heart