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CD9(MRP-1) antibody
| Antigen | CD9(MRP-1) |
| Clonality | Monoclonal (6D11) |
| Host |
Mouse |
| Reactivity |
Human |
| Application |
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
|
| Catalog no. | ABIN290054 |
| Quantity | 50 ug (0.25 mg/ml) |
| Price | 942.65 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Immunogen | human cancer cel line |
| Format | Affinity-purified |
| Isotype | IgG2a kappa (Matching secondary antibodies) |
| Clone | 6D11 |
| Description | CD9 (also known as MRP-1: Motility-Related Protein 1) is a member of tetraspanin family. Tetraspanins comprise a family of over 30 membrane glycoproteins with four hydrophobic transmembrane domains. It has been reported that tetraspanins can regulate several biological andpathological process, including migration and metastasis, adhesion, cell proliferation, differentiation. The expression of many member of the familyis changed in different types of carcinomas.Clinical and pathologic findings indicate that down-regulation of CD9 correlates with tumor progression and metastasis, including melanoma, breast,lung, colon, prostate, pancreas and ovarian cancer. Moreover, transfection of CD9 inhibits cell motility and tumor metastasis.This antibody is specific to human CD9 and will be useful for FCM, immunoprecipitation, immunohistochemistry, western blotting. |
Application Details
| Application Notes | WB 1.0-5.0 ug/ml. IHC 10.0 ug/ml. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml |
| Concentration | 0.25 mg/ml |
| Purification | Protein G |
| Buffer | PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat) |
| Storage | Store below -20 |
| Restrictions | For Research Use only |
