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Antibodies
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anti-Intercellular Adhesion Molecule 1 (ICAM1) antibody
Intercellular Adhesion Molecule 1 (ICAM1) antibody
| Antigen |
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| Synonyms |
BB2, CD54, P3.58, Ly-47, Icam-1, MALA-2, MGC6195, ICAM-1, ICAM1, ICAM |
| Clonality |
Monoclonal (YUK11) |
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Host
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Reactivity
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Human (338), Mouse (Murine) (141), Rat (Rattus) (97), Cow (Bovine) (56), Pig (Porcine) (44), Rabbit (43), Dog (Canine) (38), Sheep (Ovine) (18), Horse (Equine) (16), Chicken (4), Guinea Pig (2), Fish (1)
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Application
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 Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP)
Flow Cytometry (FACS) (327), Immunofluorescence (IF) (135), Western Blotting (WB) (126), Immunoprecipitation (IP) (80), Immunohistochemistry (Frozen Sections) (IHC (fro)) (76), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (62), ELISA (61), Immunohistochemistry (IHC) (20), Functional Studies (Func) (19), Enzyme Immunoassay (EIA) (14), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (12), Immunocytochemistry (ICC) (11), Blocking Antibody (Inhibition) (10), Immunoelectron Microscopy (IEM) (7), Blocking Antibody (Inhibition) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), ELISA (Detection) (2)
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| Catalog no. |
ABIN290055 |
| Quantity |
50 ug (0.25 mg/ml) |
| Price |
942.65 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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CD54(ICAM-1)
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Immunogen
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human cancer cel line
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Format
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Affinity-purified
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Isotype
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IgG2a kappa (Matching secondary antibodies)
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Clone
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YUK11
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Description
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CD54 (also known as ICAM-1: intercellular adhesion molecule-1) is a transmembrane glycoprotein of the immunoglobulin superfamily ofadhesion molecules. CD54 expression is constitutive on many cell types. CD54 is a inducible ligand for LFA-1 (lymphocyte function associatedantigen) and functions cell-to-cell interactions in inflammatory and immune responses.Some studies have showed that the elevated expression of CD54 occurred in a variety of diseases, including autoimmune diseases, endocrinediseases, and some cancers as gastric, pancreatic, breast cancer. Surface expressed CD54 is apparently shed from the cells and then circulatesas soluble ICAM-1 (sICAM-1). sICAM-1 can compete with cell surface CD54 to bind LFA-1 on T lymphocytes. Shedding of CD54 by circulatingtumor cells may allow their escape from surveillance by cytotoxic T and natural killer cells, and promote metastasis. It has been suggested thatsICAM-1 levels were found to be related tumor presence, clinical stages, and grade.This antibody is specific to human CD54 and will be useful for FCM, immunoprecipitation.
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Application Notes
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WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml
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Concentration
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0.25 mg/ml
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Purification
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Protein G
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Buffer
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PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
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Storage
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Store below -20
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Restrictions
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For Research Use only
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Alternatives for antigen "Intercellular Adhesion Molecule 1 (ICAM1)", type "Antibodies"
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Hosts
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Mouse (189), Rabbit (182), Rat (53), Hamster (4), Sheep (1)
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Reactivities
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Human (338), Mouse (Murine) (141), Rat (Rattus) (97), Cow (Bovine) (56), Pig (Porcine) (44), Rabbit (43), Dog (Canine) (38), Sheep (Ovine) (18), Horse (Equine) (16), Chicken (4), Guinea Pig (2), Fish (1)
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Applications
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Flow Cytometry (FACS) (327), Immunofluorescence (IF) (135), Western Blotting (WB) (126), Immunoprecipitation (IP) (80), Immunohistochemistry (Frozen Sections) (IHC (fro)) (76), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (62), ELISA (61), Immunohistochemistry (IHC) (20), Functional Studies (Func) (19), Enzyme Immunoassay (EIA) (14), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (12), Immunocytochemistry (ICC) (11), Blocking Antibody (Inhibition) (10), Immunoelectron Microscopy (IEM) (7), Blocking Antibody (Inhibition) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), ELISA (Detection) (2)
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Conjugates
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Biotin (42), FITC (38), PE (29), Alexa Fluor 488 (8), Alexa Fluor 350 (7), Alexa Fluor 555 (7), Alexa Fluor 647 (7), Cy3 (7), Cy5 (7), Cy5.5 (7), Cy7 (7), Gold (7), HRP (7), PE,Cy3 (7), PE,Cy5 (7), PE,Cy5.5 (7), PE,Cy7 (7), RBITC (7), RPE (7), APC (6), Alexa Flour 488 (6), Alexa Fluor 700 (1), Pacific Blue (1), PerCP (1)
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Epitopes
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pTyr512 (9), C-Term (2), AA 253-267 (1), Domain D1 (1)
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