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CD59(HRF20) antibody
| Antigen | CD59(HRF20) |
| Clonality | Monoclonal (YUK1) |
| Host |
Mouse |
| Reactivity |
Human |
| Application |
Flow Cytometry (FACS), Immunoprecipitation (IP)
|
| Catalog no. | ABIN290056 |
| Quantity | 50 ug (0.25 mg/ml) |
| Price | 942.65 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Immunogen | human cancer cel line |
| Format | Affinity-purified |
| Isotype | IgG1 kappa (Matching secondary antibodies) |
| Clone | YUK1 |
| Description | CD59 (also known as HRF20: 20KDa-Homologous restriction factor) is an about 20 kDa glycoprotein and member of membrane-boundcomplement-regulatory protein (CRP), and prevents formation of the membrane attack complex (MAC) in the terminal stages of complementactivation. CRPs inhibit complement-mediated killing of host cells by host complement. It has been also showed that p53 regulates cellularresistance to complement lysis through enhanced expression of CD59.CRPs are often elevated in malignancy, and enable tumor cells to escape from complement-dependent cytotoxicity. Therefore, expression,overexpression, or loss of these molecules may function as markers of tumor progression and prognosis.This antibody is specific to human CD59 and will be useful for FCM, immunoprecipitation |
Application Details
| Application Notes | WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 5.0-10.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml |
| Concentration | 0.25 mg/ml |
| Purification | Protein G |
| Buffer | PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat) |
| Storage | Store below -20 |
| Restrictions | For Research Use only |
