Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody

Antigen: Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2)

Synonyms: Mdu1, MGC53951, slc3a2, MGC53965, SLC3A2, MGC127541, MGC142823, DKFZp469L1516

Clonality: Monoclonal (WK4)

Host: Mouse

Reactivity: Human

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Catalog no.: ABIN290058

Additional Information

Alternative name: CD98hc (4F2)

Immunogen: human cancer cel line

Format: Affinity-purified

Isotype: IgG2a kappa  (Matching secondary antibodies)

Clone: WK4

Description: CD98 (also known as 4F2) is widely expressed cell surface around 120-kDa heterodimetric protein. CD98 is composed a common type IItransmembrane heavy chain of around 80-kDa (also kwon as CD98hc, 4F2hc or SLC3A2) and one of at least six light chains of around 40-kDa (LAT1,LAT2, y+LAT1, y+LAT2, xCT, asc) to form amino acid transporters. It is thought that the heavy chain is mainly involved in the trafficking of the complexto the plasma membrane, whereas the light chain catalyses the transport itself. CD98hc is a multifunctional glycoprotein, and was originally discoveredas a T-cell activation antigen. CD98hc is highly expressed on proliferating lymphocytes, tumor cells and on the other rapidly-growing cells. It has alsoshown that CD98hc has an important role in integrin-dependent signals that promote tumorigenesis.This antibody is specific to human CD98hc and will be useful for FCM, immunoprecipitation.

Application Details

Application Notes: WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 0.5-1.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml

Concentration: 0.25 mg/ml

Purification: Protein G

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Storage: Store below -20

Restrictions: For Research Use only