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ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3) antibody
| Antigen | ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3) |
| Synonyms | CD298, ATPB-3, FLJ29027 |
| Clonality | Monoclonal (5G10) |
| Host |
Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
|
| Catalog no. | ABIN290059 |
| Quantity | 50 ug (0.25 mg/ml) |
| Price | 942.65 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | CD298 (Na/K-ATPase b3) |
| Immunogen | human cancer cel line |
| Format | Affinity-purified |
| Isotype | IgG2a kappa (Matching secondary antibodies) |
| Clone | 5G10 |
| Description | Na/K-ATPase is a membrane-associated enzyme responsible for the active transport of Na + and K+, and the maintenance of Na+ and K+ gradients across membrane. It is a heterodimer of two different kinds subunit, a large alpha subunit and a smaller glycoprotein subunit beta. At least four distinct alpha subunits and four beta subunit isoforms have been identified. In some tissues, it has been showed that Na/K-ATPase is associated with third subunit gamma, a small regulatory protein. CD298 (also known as Na/K-ATPase beta3) is a 42-kDa glycoprotein and one of beta subunit isoforms. CD298 has been detected in amphibians, mouse, rat,and human. In rat, CD298 expresses in a variety of tissues including testis, brain, kidney, spleen, stomach, small intestine, colon, lung, and liver. In theretina Na/K-ATPase restores Na+ and K+ gradients used by photoreceptor dark current, synaptic activity, action potential, and CD298 is largely restricted to photoreceptors in the mouse and rat. In human, CD298 also involves in regulation of T and B lymphocyte proliferation.This antibody is specific to human CD298 and will be useful for FCM, immunoprecipitation, immunohistochemistry. |
Application Details
| Application Notes | WB Not tested. IHC 5.0-10.0 ug/ml. ICC Not tested. ELISA Not tested. FCM 0.5-1.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml |
| Concentration | 0.25 mg/ml |
| Purification | Protein G |
| Buffer | PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat) |
| Storage | Store below -20 |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3)", type "Antibodies"
| Hosts | Mouse (10), Rabbit (2) |
| Reactivities | Human (12) |
| Applications | Enzyme Immunoassay (EIA) (5), Western Blotting (WB) (5), ELISA (Detection) (3), ELISA (2), Flow Cytometry (FACS) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |




Alternatives