KOR antibody
| Antigen |
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| Clonality |
Monoclonal (5E3) |
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Host
|
|
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Reactivity
|
Human
|
|
Application
|
Alternatives Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
|
| Catalog no. |
ABIN290066 |
| Quantity |
25 ug (0.25 mg/ml) |
| Price |
942.65 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Immunogen
|
hKOR expressing cell line
|
|
Format
|
Affinity-purified
|
|
Isotype
|
IgG1 kappa (Matching secondary antibodies)
|
|
Clone
|
5E3
|
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Description
|
OPRK1 (opioid receptor, kappa 1), also known as KOR, belongs to the rhodopsin subfamily of G-protein-coupled receptor (GPCR) family. OPRK1 is consist of 380amino acids and is widely expressed in the nervous system. OPRK1 is activated by endogenous opioid peptide agonists derived from prodynorphin. Stimulation ofOPRK1 in vivo produces many effects, including analgesia, water diuresis, dysphoria, antipruritic effects, and attenuation of cocaine craving in addicts. In addition,some studies reported that OPRK1 is associated with alcohol intake and the risk for alcohol dependence and activation of OPRK1 in human microglia suppressesHIV-1 expression.
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Application Notes
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WB 5.0 ug/ml. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0 ug/ml. Neutralization Not tested. IP 5.0 ug/ml.
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Concentration
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0.25 mg/ml
|
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Purification
|
Protein G
|
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Buffer
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PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
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Storage
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Store below -20
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Restrictions
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For Research Use only
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Alternatives for antigen "KOR", type "Antibodies"