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Product Details

anti-Histone H1 antibody

Overview

Antigen: Histone H1
Clonality: Monoclonal (AE-4)
Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Reactivity: Human
Host: Mouse
Quantity: 200 µg (1 mg/ml)
Price: 460,00 $   (Plus shipping costs $25 and VAT, Invoice in EUR)
Order number: ABIN291574
Availability: Ships within 10 to 15 Business days
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Additional Information  » anti-Histone H1 antibody

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Antigen Histone H1
Immunogen Nuclei from myeloid leukemia biopsy cells
Reactivity Human
Clonality Monoclonal
Isotype IgG2a »Matching secondary antibodies
Description Gene: Histone H1.
Clone AE-4
Host Mouse
Specificity Recognizes histone H1. The histone proteins serve as a structural scaffold for the organization of nuclear DNA into chromatin. In eukaryotic cells there are 4 core histone proteins, H2A, H2B, H3 and H4 that assemble to form an octamer round which the DNA is wrapped in a sequence dependant manner. The resulting complex is known as a nucleosome and is the basic subunit of chromatin. Histone H1 acts as a linker and binds to each nucleosome, and by self affinity, links these nucleosomes together resulting in the 30 nm chromatin fiber. In blots of rat brain homogenate a duplet is observed at 27-29 kD consistent with Histone H1. Speckled staining is observed in the nucleus of normal and malignant cells.

Application Details  » anti-Histone H1 antibody

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Application Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
» Click here to view 4 available protocols!
Application Notes WB (1:100), ELISA, IF, IHC-P, IHC-Fr
Concentration 1 mg/ml
Purification Protein G Column
Buffer PBS, 0.09% sodium azide.
Storage Long term: -20°C, Short term: -20°C
Restrictions For Research Use only