PLG antibody

Catalog No. ABIN291707

Product Details anti-PLG Antibody

Target: PLG (Plasminogen (PLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLG antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes human plasminogen, a single chain beta globulin of 80-90kD. It is a circulating zymogen that is converted to the active enzyme plasmin (fibrinolysin) by plasminogen activators. The main function of plasmin is to dissolve fibrin and thus break up blood clots. Plasmin also plays a proteolytic role in processes such as embryonic development, tissue remodeling, tumor invasion and inflammation. Plasminogen deficiency may be a cause of thrombosis, or may be acquired through acute liver disease, acute disseminated intravascular coagulation or through thrombolytic therapy with plasminogen activators. Does not cross-react with other human serum proteins.

Purification: Ion exchange chromatography

Immunogen: Purified human plasminogen.

Type of Immunogen: Purified protein

Clone: 4D2

Isotype: IgG2b

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P

Usage: Immunohistology: This product does not require protein digestion pre-treatment of paraffin embedded sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for PLG

Target: PLG (Plasminogen (PLG))

Alternative Name: PLG / Plasmin / Plasminogen (PLG Products)

Synonyms: wu:fb70e09 antibody, PLG antibody, LPA antibody, plg antibody, Ab1-346 antibody, AI649309 antibody, Pg antibody, plasminogen antibody, plg antibody, PLG antibody, Plg antibody

Background: Name/Gene ID: PLG
Subfamily: Serine S1
Family: Protease

Synonyms: PLG, Plasmin, Plasminogen

Gene ID: 5340

Pathways: Complement System, Lipid Metabolism