DcR2 antibody (AA 1-210)
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- Target See all DcR2 (TNFRSF10D) Antibodies
- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
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Binding Specificity
- AA 1-210
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DcR2 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
- Clone
- TRAIL-R4-01
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF10D Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibody
TNFRSF10D Reactivity: Human, Mouse WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 6E5A9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibodyTNFRSF10D Reactivity: Human, Monkey WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 6G7G1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibodyTNFRSF10D Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (FITC)TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibodyTNFRSF10D Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 252-278) antibodyTNFRSF10D Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB24080 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (APC)TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (PE)TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263) antibodyTNFRSF10D Reactivity: Human, Mouse, Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 257-386) antibodyTNFRSF10D Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Preservative
- Azide free
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
- Alternative Name
- CD264 / TRAIL-R4 (TNFRSF10D Products)
- Synonyms
- TNFRSF10D antibody, CD264 antibody, DCR2 antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, TNF receptor superfamily member 10d antibody, tumor necrosis factor receptor superfamily member 10D antibody, TNFRSF10D antibody, LOC716901 antibody
- Background
- TNF receptor superfamily member 10d,TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).,TNFRSF10D, DcR2, TRUNDD, TRAILR4
- Gene ID
- 8793
- UniProt
- Q9UBN6
- Pathways
- Apoptosis
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