Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LRP5 antibody (AA 1000-1250)

LRP5 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1513164
  • Target See all LRP5 Antibodies
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    Binding Specificity
    • 17
    • 15
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1000-1250
    Reactivity
    • 59
    • 45
    • 22
    • 1
    • 1
    Human
    Host
    • 67
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 70
    • 4
    Polyclonal
    Conjugate
    • 26
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LRP5 antibody is un-conjugated
    Application
    • 43
    • 38
    • 26
    • 20
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    IKRAKDDGTQ PFVLTSLSQG QNPDRQPHDL SIDIYSRTLF WTCEATNTIN VHRLSGEAMG VVLRGDRDKP RAIVVNAERG YLYFTNMQDR AAKIERAALD GTEREVLFTT GLIRPVALVV DNTLGKLFWV DADLKRIESC DLSGANRLTL EDANIVQPLG LTILGKHLYW IDRQQQMIER VEKTTGDKRT RIQGRVAHLT GIHAVEEVSL EEFSAHPCAR DNGGCSHICI AKGDGTPRCS CPVHLVLLQN L
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." in: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

  • Target
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    Alternative Name
    LRP5 (LRP5 Products)
    Synonyms
    Xlrp5 antibody, bmnd1 antibody, evr1 antibody, evr4 antibody, hbm antibody, lr3 antibody, lrp5-A antibody, lrp7 antibody, oppg antibody, ops antibody, opta1 antibody, vbch2 antibody, LRP5 antibody, LRP6 antibody, BMND1 antibody, EVR1 antibody, EVR4 antibody, HBM antibody, LR3 antibody, LRP7 antibody, OPPG antibody, OPS antibody, OPTA1 antibody, VBCH2 antibody, mKIAA4142 antibody, low-density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 antibody, LDL receptor related protein 5 L homeolog antibody, low density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 like antibody, LOC100147353 antibody, LRP5 antibody, lrp5.L antibody, lrp5 antibody, Lrp5 antibody, LRP5L antibody
    Background
    This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.,LRP5,BMND1,EVR1,EVR4,HBM,LR3,LRP-5,LRP7,OPPG,OPS,OPTA1,VBCH2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Extracellular Matrix,Bone,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Stem Cells,Cardiovascular,Lipids,LRP5
    Molecular Weight
    179 kDa
    Gene ID
    4041
    UniProt
    O75197
    Pathways
    WNT Signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
You are here:
Support