MAD1L1 antibody (AA 360-700)

Catalog No. ABIN3021566

Product Details anti-MAD1L1 Antibody

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Binding Specificity: AA 360-700

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD1L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: RGLEKARQQL QEELRQVSGQ LLEERKKRET HEALARRLQK RVLLLTKERD GMRAILGSYD SELTPAEYSP QLTRRMREAE DMVQKVHSHS AEMEAQLSQA LEELGGQKQR ADMLEMELKM LKSQSSSAEQ SFLFSREEAD TLRLKVEELE GERSRLEEEK RMLEAQLERR ALQGDYDQSR TKVLHMSLNP TSVARQRLRE DHSQLQAECE RLRGLLRAME RGGTVPADLE AAAASLPSSK EVAELKKQVE SAELKNQRLK EVFQTKIQEF RKACYTLTGY QIDITTENQY RLTSLYAEHP GDCLIFKATS PSGSKMQLLE TEFSHTVGEL IEVHLRRQDS I

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MAD1/MAD1/MAD1L1 (NP_001013859.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAD1L1

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Alternative Name: MAD1L1 (MAD1L1 Products)

Synonyms: MAD1 antibody, PIG9 antibody, TP53I9 antibody, TXBP181 antibody, AI173502 antibody, AW550425 antibody, Mad1 antibody, zgc:56571 antibody, MAD1-like protein 1 antibody, mitotic arrest deficient 1 like 1 antibody, MAD1 mitotic arrest deficient like 1 antibody, MAD1 mitotic arrest deficient 1-like 1 antibody, deafness, autosomal recessive 19 antibody, MAD1L1 antibody, Mad1l1 antibody, mad1l1 antibody, DFNB19 antibody

Background: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.,MAD1L1,MAD1,PIG9,TP53I9,TXBP181,Cell Biology & Developmental Biology,Cell Cycle,Centromere,MAD1L1

Molecular Weight: 72 kDa/83 kDa

Gene ID: 8379

UniProt: Q9Y6D9

Pathways: M Phase