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Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
| Antigen | Caveolin 1, Caveolae Protein, 22kDa (CAV1) |
| Synonyms | CAV, CGL3, BSCL3, VIP21, MSTP085, Cav, Cav-1, MGC187299, CAV1, fc07c04, wu:fc07c04, cav1a, cav1b, caveolin 1, cav, vip21, mstp085, MGC107940, Caveolin-1, cav1 |
| Epitope |
 Alternatives N-Term |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus) |
| Application |
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|
| Catalog no. | ABIN302394 |
| Quantity | 50 µg (1.0 mg/ml) (Variants) |
| Price | 390.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: CAV1 |
| Alternative name | Caveolin-1 (N-term) |
| Swiss-Prot | Q03135 |
| Immunogen | CAV1 antibody was raised against Synthetic peptide - KLH conjugated, N-term of HumanRemarks: Mouse Identity: 100%Mouse Similarity: 100%Rat Identity: 100%Rat Similarity: 100% |
| Description | Caveolin 1 is the main component of the caveolae plasma membranes found in most celltypes. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosinekinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promotingcell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulatorof the Ras-p42/44 MAP kinase cascade. |
| Specificity | This antibody detects Caveolin-1 (CAV1), N-terminal region. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse and Rat. |
Application Details
| Application Notes | Immunohistochemistry on Paraffin Sections (3 µg/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 1.0 mg/ml |
| Buffer | PBS containing 0.09% Sodium Azide as preservative. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C forlonger. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Caveolin 1, Caveolae Protein, 22kDa (CAV1)", type "Antibodies"
| Hosts | Rabbit (68), Goat (8), Mouse (6), Sheep (2) |
| Reactivities | Human (72), Rat (Rattus) (51), Mouse (Murine) (49), Dog (Canine) (6), Pig (Porcine) (5), Hamster (1) |
| Applications | Western Blotting (WB) (53), Immunofluorescence (IF) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20), Flow Cytometry (FACS) (13), Enzyme Immunoassay (EIA) (12), ELISA (11), Immunohistochemistry (IHC) (6), Immunoprecipitation (IP) (6), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (EM) (1) |
| Conjugates | Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | pTyr14 (10), N-Term (7), C-Term (5), 1t cytoplasmic domain (4), internal (2), Y14 (1), non pTyr14 (1), pY14 (1) |
