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Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody

Antigen

Caveolin 1, Caveolae Protein, 22kDa (CAV1)
Synonyms CAV, CGL3, BSCL3, VIP21, MSTP085, Cav, Cav-1, MGC187299, CAV1, fc07c04, wu:fc07c04, cav1a, cav1b, caveolin 1, cav, vip21, mstp085, MGC107940, Caveolin-1, cav1
Epitope
Alternatives

N-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN302396
Quantity 50 µg  (1.0 mg/ml)  (Variants)
Price 390.00 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: CAV1
Alternative name Caveolin-1
Swiss-Prot Q03135
Immunogen Synthetic peptide - KLH conjugated, N-terminal of humanRemarks: Mouse Identity: 93 %Mouse Similarity: 100 %Rat Identity: 93 %Rat Similarity: 100 %
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Description Caveolin 1 is the main component of the caveolae plasma membranes found in most celltypes. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosinekinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promotingcell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulatorof the Ras-p42/44 MAP kinase cascade.
Specificity This antibody detects Caveolin-1 (CAV1), N-terminal region. Species: Human, Mouse, Rat. Others not tested. Add. Information: Mouse Identity: 93 %Mouse Similarity: 100 %Rat Identity: 93 %Rat Similarity: 100 %

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Immunohistochemistry on paraffin sections (17 ug/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer Phosphate buffered saline containing 0.09% sodium azide
Storage Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Caveolin 1, Caveolae Protein, 22kDa (CAV1)", type "Antibodies"
Hosts Rabbit (78), Goat (8), Mouse (7), Sheep (2)
Reactivities Human (80), Rat (Rattus) (55), Mouse (Murine) (49), Dog (Canine) (8), Pig (Porcine) (5), Cow (Bovine) (2), Horse (Equine) (2), Chicken (1), Hamster (1), Rabbit (1)
Applications Western Blotting (WB) (60), Immunofluorescence (IF) (31), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (21), Flow Cytometry (FACS) (18), Enzyme Immunoassay (EIA) (13), ELISA (11), Immunohistochemistry (IHC) (7), Immunoprecipitation (IP) (7), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pTyr14 (10), N-Term (7), C-Term (5), 1t cytoplasmic domain (4), Y14 (1), internal (1), pY14 (1)