CLEC1A antibody (N-Term)

Catalog No. ABIN3024556

Product Details anti-CLEC1A Antibody

Target: CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC1A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A purified antibody

Immunogen: A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CLEC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CLEC1A

Target: CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))

Alternative Name: CLEC1 (CLEC1A Products)

Synonyms: RGD1566110 antibody, CLEC1 antibody, 5930406N14Rik antibody, C-type lectin domain family 1, member A antibody, C-type lectin domain family 1 member A antibody, C-type lectin domain family 1, member a antibody, Clec1a antibody, CLEC1A antibody

Background: CLEC1 is a C-type lectin receptor and part of the 'Dectin-1 cluster' subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.

Gene ID: 51267