DUSP23 antibody (Internal Region)

Catalog No. ABIN302514

Product Details anti-DUSP23 Antibody

Target: DUSP23 (Dual Specificity Phosphatase 23 (DUSP23))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP23 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects Dual Specificity Phosphatase 23 (DUSP23) at internal domain.

Purification: Immunoaffinity Chromatography

Immunogen: DUSP23 antibody was raised against synthetic peptide from internal domain of human DUSP23.

Application Details

Application Notes: Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for DUSP23

Target: DUSP23 (Dual Specificity Phosphatase 23 (DUSP23))

Alternative Name: DUSP23 (DUSP23 Products)

Synonyms: DUSP23 antibody, vhz antibody, mosp antibody, ldp-3 antibody, dusp25 antibody, DUSP25 antibody, LDP-3 antibody, MOSP antibody, RP11-190A12.1 antibody, VHZ antibody, 1300005N15Rik antibody, dual specificity phosphatase 23 antibody, dual specificity phosphatase 23 L homeolog antibody, Dusp23 antibody, DUSP23 antibody, dusp23.L antibody, dusp23 antibody

Background: Most of dual-specificity protein phosphatases (DSPs) play an important role in the regulation of mitogenic signal transduction and controlling the cell cycle in response to extracellular stimuli . DUSP23 has been shown to dephosphorylate p44ERK1 but not p38 and p54SAPKbeta in vitro. Reverse transcription-PCR (RT-PCR) revealed that the DUSP23 was expressed in most fetal tissues and two adult tissues: testis and colon.Synonyms: Dual specificity protein phosphatase 23, LDP3, Low molecular mass dual specificity phosphatase 3, VH1-like phosphatase Z, VHZ

Gene ID: 54935

NCBI Accession: NP_060293

UniProt: Q9BVJ7