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MAPKAP1 antibody (C-Term)

MAPKAP1 Reactivity: Human, Mouse, Rat, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3025251
  • Target See all MAPKAP1 Antibodies
    MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
    Binding Specificity
    • 11
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 36
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 36
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPKAP1 antibody is un-conjugated
    Application
    • 28
    • 15
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Protein A purified antibody
    Immunogen
    A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
    Isotype
    IgG
    Top Product
    Discover our top product MAPKAP1 Primary Antibody
  • Application Notes
    Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.\. Western blot: 1-3 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.
  • Target
    MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
    Alternative Name
    SIN1 (MAPKAP1 Products)
    Synonyms
    CG10105 antibody, Dmel\\CG10105 antibody, dSin1 antibody, sin1 antibody, MAPKAP1 antibody, im:7143088 antibody, si:ch73-242f23.1 antibody, mip1 antibody, sin1b antibody, sin1g antibody, MGC53034 antibody, JC310 antibody, MIP1 antibody, SIN1 antibody, SIN1b antibody, SIN1g antibody, AI591529 antibody, D230039K05Rik antibody, Sin1 antibody, SAPK-interacting protein 1 antibody, mitogen-activated protein kinase associated protein 1 antibody, mitogen-activated protein kinase associated protein 1 L homeolog antibody, Sin1 antibody, MAPKAP1 antibody, mapkap1 antibody, Mapkap1 antibody, mapkap1.L antibody
    Background
    MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
    Gene ID
    79109
    Pathways
    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
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