MUC6 antibody

Catalog No. ABIN3025271

Product Details anti-MUC6 Antibody

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC6 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

No Cross-Reactivity: Rat (Rattus)

Purification: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the Mucin-6 antibody.

Clone: MUCN6-1

Isotype: IgG1 kappa

Application Details

Application Notes: Titering of the Mucin-6 antibody may be required for optimal performance.

1. FFPE testing requires sections to be boiled in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1),Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Mucin-6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Alternative Name: Mucin-6 (MUC6 Products)

Synonyms: gastric antibody, MUC-6 antibody, mucin-6-like antibody, mucin 6, oligomeric mucus/gel-forming antibody, mucin 6, gastric antibody, LOC100850574 antibody, MUC6 antibody, Muc6 antibody

Background: Mucin 6 may provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. Highest expression seen in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. [UniProt]