EPX antibody

Catalog No. ABIN3025391

Product Details anti-EPX Antibody

Target: EPX (Eosinophil Peroxidase (EPX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPX antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: Protein G purified monoclonal antibody

Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome were used as the immunogen for this Eosinophil peroxidase antibody.

Clone: AHE-1

Isotype: IgG1 kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Eosinophil Peroxidase antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for EPX

Target: EPX (Eosinophil Peroxidase (EPX))

Alternative Name: Eosinophil Peroxidase (EPX Products)

Synonyms: EPX antibody, pmr-1 antibody, EPO antibody, EPP antibody, EPX-PEN antibody, eosinophil peroxidase antibody, eosinophil peroxidase L homeolog antibody, LOC788751 antibody, EPX antibody, epx.L antibody, Epx antibody

Background: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).

Gene ID: 8288