PTGER3 antibody (Cytoplasmic Domain)

Catalog No. ABIN302631

Product Details anti-PTGER3 Antibody

Target: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Binding Specificity: Cytoplasmic Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Prostaglandin E Receptor EP3 (PTGER3) at 3rd cytoplasmic domain.

Purification: Immunoaffinity Chromatography.

Immunogen: PTGER3 antibody was raised against synthetic peptide from 3rd cytoplasmic domain of human PTGER3 / EP3.

Application Details

Application Notes: ELISA. Immunohistochemistry on Paraffin Sections (4 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for PTGER3

Target: PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))

Alternative Name: PTGER3 (PTGER3 Products)

Synonyms: PTGER3 antibody, EP3 antibody, EP3-I antibody, EP3-II antibody, EP3-III antibody, EP3-IV antibody, EP3e antibody, PGE2-R antibody, PTGEREP3 antibody, Rep3 antibody, rEP3a antibody, rEP3b antibody, Pgerep3 antibody, Ptgerep3 antibody, prostaglandin E receptor 3 antibody, prostaglandin E receptor 3 L homeolog antibody, prostaglandin E receptor 3 (subtype EP3) antibody, PTGER3 antibody, ptger3.L antibody, Ptger3 antibody

Background: Prostaglandin E Receptor EP3 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP1, EP2, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, and asthma. Various isoforms are produced by alternative splicing.Synonyms: EP3, EP3-II, EP3-III, PGE receptor EP3 subtype, PGE2 receptor EP3 subtype, PGE2-R, Prostaglandin E receptor 3, Prostaglandin E2 receptor EP3 subtype, Prostanoid EP3 receptor

Gene ID: 5733

NCBI Accession: NP_001119516

UniProt: P43115