CBLN1 antibody (Middle Region)

Catalog No. ABIN303204

Product Details anti-CBLN1 Antibody

Target: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: 15 amino acid peptide from the middle of Human Precerebellin.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to 15 amino acid peptide from the middle of Human Precerebellin.

Application Details

Application Notes: Western Blot (2-4 μg/mL). Immunohistochemistry on Paraffin Sections (10 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Target Details for CBLN1

Target: CBLN1 (Cerebellin 1 Precursor (CBLN1))

Alternative Name: Cerebellin-1 (CBLN1 Products)

Synonyms: cbln1 antibody, zgc:92807 antibody, CBLN1 antibody, MGC145915 antibody, AI323299 antibody, cerebellin 3 precursor antibody, cerebellin 1 precursor antibody, cerebellin 1 precursor L homeolog antibody, cerebellin 1 precursor protein antibody, cbln3 antibody, cbln1 antibody, cbln1.L antibody, CBLN1 antibody, Cbln1 antibody

Background: CBLN1 is required for synapse integrity and synaptic plasticity. It is required for the ER export and secretion of CBLN3. CBLN1 exerts neuromodulatory functions. It directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway, and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release.Synonyms: CBLN1, Precerebellin

Gene ID: 869

NCBI Accession: NP_004343

UniProt: P23435