TMED10 antibody (C-Term)

Catalog No. ABIN303302

Product Details anti-TMED10 Antibody

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMED10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts to a 19 amino acid peptide from near the carboxy terminus of human TMP21.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Purified

Immunogen: Synthetic Peptide corresponding to 19 amino acid peptide from near the carboxy terminus of human TMP21.

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections (3 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for TMED10

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Alternative Name: TMED10 / TMP21 (TMED10 Products)

Synonyms: tmp21 antibody, P24(DELTA) antibody, S31I125 antibody, S31III125 antibody, TMP21 antibody, Tmp-21-I antibody, p23 antibody, 1110014C03Rik antibody, Tmp21 antibody, p24delta1 antibody, fe06g04 antibody, wu:fb98e10 antibody, wu:fe06g04 antibody, zgc:85681 antibody, transmembrane p24 trafficking protein 10 L homeolog antibody, transmembrane p24 trafficking protein 10 antibody, tmed10.L antibody, TMED10 antibody, Tmed10 antibody, tmed10 antibody

Background: TMP21 is a integral membrane protein that is localized in microsomal membranes, zymogen granule membrane and the plasma membrane. It is ubiquitously expressed and is involved in vesicular targeting and protein transport. Recent studies have shown that TMP21 is a component of presenillin complexes and differentially regulates gamma-secretase cleavage of the amyloid precursor protein, without affecting epsilon-secretase activity.Synonyms: 21 kDa transmembrane-trafficking protein, S31I125, Transmembrane emp24 domain-containing protein 10, Transmembrane protein Tmp21

Gene ID: 10972

NCBI Accession: NP_006818

UniProt: P49755