CYR61 antibody (AA 54-381)

Catalog No. ABIN3042351

Product Details anti-CYR61 Antibody

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Binding Specificity: AA 54-381

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYR61 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Protein CYR61(CYR61) detection. Tested with WB in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Protein CYR61(CYR61) detection. Tested with WB in Human,Rat.
Gene Name: cysteine-rich, angiogenic inducer, 61
Protein Name: Protein CYR61

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Alternative Name: CYR61 (CYR61 Products)

Synonyms: CCN1 antibody, GIG1 antibody, IGFBP10 antibody, ccn1 antibody, gig1 antibody, Xcyr61 antibody, igfbp10 antibody, MGC69281 antibody, MGC69539 antibody, cyr61-l2 antibody, zgc:158158 antibody, CYR61 antibody, AI325051 antibody, Igfbp10 antibody, cysteine rich angiogenic inducer 61 antibody, cysteine-rich, angiogenic inducer, 61 antibody, cysteine-rich, angiogenic inducer, 61 like 2 antibody, cysteine rich protein 61 antibody, cysteine rich angiogenic inducer 61 S homeolog antibody, CYR61 antibody, Cyr61 antibody, cyr61 antibody, cyr61l2 antibody, cyr61.S antibody

Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Synonyms: 3CH61 antibody|CCN 1 antibody|CCN family member 1 antibody|CCN1 antibody|CCN1 antibody|CYR 61 antibody|Cyr61 antibody|CYR61 protein antibody|CYR61 protein precursor antibody|CYR61 protein precursor antibody|CYR61_HUMAN antibody|Cysteine rich angiogenic inducer 61 antibody|Cysteine rich angiogenic inducer 61 antibody|Cysteine rich angiogenic inducer 61 antibody|Cysteine rich heparin binding protein 61 antibody|Cysteine-rich angiogenic inducer 61 antibody|GIG 1 antibody|GIG1 antibody|GIG1 protein antibody|GIG1 protein antibody|IBP-10 antibody|IGF-binding protein 10 antibody|Igfbp 10 antibody|IGFBP-10 antibody|IGFBP10 antibody|IGFBP10 antibody|Insulin like growth factor binding protein 10 antibody|Insulin like growth factor binding protein 10 antibody|Insulin like growth factor binding protein 10 antibody|Insulin-like growth factor-binding protein 10 antibody|Protein CYR61 antibody|Protein GIG1 antibody

Gene ID: 3491

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding