GABRB3 antibody (C-Term)

Catalog No. ABIN3042414

Product Details anti-GABRB3 Antibody

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Binding Specificity: AA 344-375, C-Term

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit beta-3(GABRB3) detection. Tested with WB in Human,Mouse, Rat.

Sequence: EKTAKAKNDR SKSESNRVDA HGNILLTSLE VH

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit beta-3(GABRB3) detection. Tested with WB in Human,Mouse, Rat.
Gene Name: gamma-aminobutyric acid (GABA) A receptor, beta 3
Protein Name: Gamma-aminobutyric acid receptor subunit beta-3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GABRB3 (344-375aa EKTAKAKNDRSKSESNRVDAHGNILLTSLEVH), different from the related mouse and rat sequences by five amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for GABRB3

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Alternative Name: GABRB3 (GABRB3 Products)

Synonyms: GABRB3 antibody, eca5 antibody, LOC100230475 antibody, ECA5 antibody, A230092K12Rik antibody, AW049585 antibody, Cp1 antibody, Gabrb-3 antibody, beta3 antibody, gamma-aminobutyric acid type A receptor beta3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, beta 3 antibody, gamma-aminobutyric acid type A receptor beta 3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 antibody, GABRB3 antibody, gabrb3 antibody, Gabrb3 antibody

Background: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. And this gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. It may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Synonyms: ECA5 antibody|GABA A receptor beta 3 subunit antibody|GABA A receptor subunit beta 3 antibody|GABA alpha receptor beta 3 subunit antibody|GABA alpha receptor beta-2 subunit antibody|GABA(A) receptor beta 3 subunit antibody|GABA(A) receptor subunit beta 3 antibody|GABA(A) receptor subunit beta-3 antibody|GABAA receptor beta 3 subunit antibody|GABAA receptor subunit beta 3 antibody|GABR B3 antibody|GABRB 3 antibody|GABRB3 antibody|Gamma aminobutyric acid (GABA) A receptor beta 3 antibody|Gamma aminobutyric acid A receptor beta 3 antibody|Gamma aminobutyric acid receptor subunit beta 3 antibody|Gamma-aminobutyric acid receptor subunit beta-3 antibody|GBRB3_HUMAN antibody|MGC9051 antibody

Gene ID: 2562

UniProt: P28472

Pathways: Sensory Perception of Sound