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HSPB2 antibody (AA 1-182)

HSPB2 Reactivity: Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042465
  • Target See all HSPB2 Antibodies
    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
    Binding Specificity
    • 15
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-182
    Reactivity
    • 44
    • 27
    • 26
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Rat
    Host
    • 58
    • 2
    Rabbit
    Clonality
    • 58
    • 2
    Polyclonal
    Conjugate
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSPB2 antibody is un-conjugated
    Application
    • 47
    • 20
    • 19
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Heat shock protein beta-2(HSPB2) detection. Tested with WB in Human,Rat.
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Heat shock protein beta-2(HSPB2) detection. Tested with WB in Human,Rat.
    Gene Name: heat shock 27 kDa protein 2(HspB2)
    Protein Name: Heat shock protein beta-2
    Purification
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human HSPB2 recombinant protein (Position: M1-P182). Human HSPB2 shares 97.3% amino acid (aa) sequence identity with both mouse and rat HSPB2.
    Isotype
    IgG
    Top Product
    Discover our top product HSPB2 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
    Alternative Name
    HSPB2 (HSPB2 Products)
    Synonyms
    zgc:112532 antibody, HSP27 antibody, Hs.78846 antibody, LOH11CR1K antibody, MKBP antibody, 27kDa antibody, 2810021G24Rik antibody, heat shock protein family B (small) member 2 antibody, heat shock protein, alpha-crystallin-related, b2 antibody, heat shock protein 2 antibody, HSPB2 antibody, hspb2 antibody, Hspb2 antibody
    Background
    Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein (HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al. (1997) identified a gene transcribed in the opposite direction. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al. (1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2 is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.

    Synonyms: DMPK-binding protein antibody|Heat shock 27kD protein 2 antibody|Heat shock 27 kDa protein 2 antibody|Heat shock protein beta-2 antibody|Heat-shock protein beta-2 antibody|Hs.78846 antibody|HSP27 antibody|HspB2 antibody|HSPB2_HUMAN antibody|LOH11CR1K antibody| MGC133245 antibody|MKBP antibody
    Gene ID
    3316
    UniProt
    Q16082
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