KAT2A antibody (N-Term)

Catalog No. ABIN3042472

Product Details anti-KAT2A Antibody

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Binding Specificity: AA 75-106, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Histone acetyltransferase KAT2A(KAT2A) detection. Tested with WB in Human.

Sequence: DPARPGLSQQ QRASQRKAQV RGLPRAKKLE KL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Histone acetyltransferase KAT2A(KAT2A) detection. Tested with WB in Human.
Gene Name: K(lysine) acetyltransferase 2A
Protein Name: Histone acetyltransferase KAT2A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human KAT2A/GCN5 (75-106aa DPARPGLSQQQRASQRKAQVRGLPRAKKLEKL), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A (KAT2A Products)

Synonyms: KAT2A antibody, GCN5L2 antibody, GCN5 antibody, PCAF-b antibody, hGCN5 antibody, 1110051E14Rik antibody, AW212720 antibody, Gcn5 antibody, Gcn5l2 antibody, mmGCN5 antibody, K(lysine) acetyltransferase 2A antibody, lysine acetyltransferase 2A antibody, histone acetyltransferase KAT2A antibody, ras-related protein Rab-5C antibody, KAT2A antibody, LOC100176452 antibody, LOC100597293 antibody, Kat2a antibody

Background: Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene. It is mapped to 17q21. KAT2A, or GCN5, GCN5L2, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex. The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.

Synonyms: 1110051E14Rik antibody|AW212720 antibody|EC 2.3.1.48 antibody|GCN 5 antibody|GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 antibody|Gcn5 antibody|GCN5 general control of amino-acid synthesis 5-like 2 (yeast) antibody|GCN5L2 antibody|general control of amino acid synthesis 5-like 2 antibody|General control of amino acid synthesis protein 5-like 2 antibody|General control of amino acid synthesis, yeast, homolog-like 2 antibody|HGCN5 antibody|Histone acetyltransferase GCN5 antibody|Histone acetyltransferase KAT2A antibody|hsGCN5 antibody|K(lysine) acetyltransferase 2A antibody|KAT2 A antibody|KAT2A antibody|KAT2A_HUMAN antibody|Lysine acetyltransferase 2A antibody|MGC102791 antibody|PCAF-b antibody|STAF97 antibody

Gene ID: 2648

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation