LOX antibody (Middle Region)

Catalog No. ABIN3042506

Product Details anti-LOX Antibody

Target: LOX (Lysyl Oxidase (LOX))

Binding Specificity: AA 240-268, Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for Protein-lysine 6-oxidase(LOX) detection. Tested with WB, ELISA in Human,Mouse,Rat.

Sequence: AEENCLASTA YRADVRDYDH RVLLRFPQR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Protein-lysine 6-oxidase(LOX) detection. Tested with WB, ELISA in Human,Mouse,Rat.
Gene Name: lysyl oxidase
Protein Name: Protein-lysine 6-oxidase

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human LOX (240-268aa AEENCLASTAYRADVRDYDHRVLLRFPQR), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: LOX (LOX Products)

Synonyms: LOX antibody, Xlox antibody, MGC146507 antibody, lox antibody, zgc:77447 antibody, AI893619 antibody, TSC-160 antibody, H-rev142 antibody, Rrg1 antibody, lysyl oxidase antibody, lysyl oxidase a antibody, lysyl oxidase L homeolog antibody, LOX antibody, lox antibody, loxa antibody, lox.L antibody, Lox antibody

Background: Lysyl oxidase (LOX), also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the LOX gene. The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: lox antibody|LYOX antibody|LYOX_HUMAN antibody|Lysyl oxidase antibody|MGC105112 antibody|Protein lysine 6 oxidase antibody|Protein-lysine 6-oxidase antibody

Gene ID: 4015

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome