TRPC4 antibody (C-Term)

Catalog No. ABIN3042531

Product Details anti-TRPC4 Antibody

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Binding Specificity: AA 961-977, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 4(TRPC4) detection. Tested with WB in Human.

Sequence: LNLPDTVTHE DYVTTRL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 4(TRPC4) detection. Tested with WB in Human.
Gene Name: transient receptor potential cation channel, subfamily C, member 4
Protein Name: Short transient receptor potential channel 4

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRPC4(961-977aa LNLPDTVTHEDYVTTRL).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TRPC4

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Alternative Name: TRPC4 (TRPC4 Products)

Synonyms: TRPC5 antibody, TRPC4 antibody, HTRP-4 antibody, HTRP4 antibody, TRP4 antibody, CCE1 antibody, STRPC4 antibody, Trp4 antibody, Trrp4 antibody, transient receptor potential cation channel subfamily C member 4 antibody, short transient receptor potential channel 4 antibody, transient receptor potential cation channel, subfamily C, member 4 antibody, TRPC4 antibody, LOC100538928 antibody, trpc4 antibody, Trpc4 antibody

Background: The short transient receptor potential channel 4(TRPC4), also known as Trp-related protein 4, is a protein that in humans is encoded by the TRPC4 gene. TRPC4 is a member of the transient receptor potential cation channels. It is mapped to 13q13.3. This protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors andtyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. TRPC4 also has an essential role in endothelial-dependent regulation of vascular tone, endothelial permeability, and neurotransmitter release from thalamic interneurons.

Synonyms: CCE1 antibody|HTRP 4 antibody|hTrp-4 antibody|HTRP4 antibody|MGC119570 antibody|MGC119571 antibody|MGC119572 antibody|MGC119573 antibody|RP11-10M8.1 antibody|Short transient receptor potential channel 4 antibody|STRPC4 antibody|Transient receptor potential 4 antibody|transient receptor potential cation channel subfamily C antibody|Transient receptor potential cation channel subfamily C member 4 antibody|transient receptor potential channel 4 antibody|TRP 4 antibody|trp related protein 4 antibody|Trp-related protein 4 antibody|TRP4 antibody|TRPC 4 antibody|TrpC4 antibody|TRPC4 protein antibody|TRPC4_HUMAN antibody