KCNA1 antibody (C-Term)

Catalog No. ABIN3042542

Product Details anti-KCNA1 Antibody

Target: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Binding Specificity: AA 465-481, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNA1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 1(KCNA1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: IAHYRQVNIR TANCTTA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 1(KCNA1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: potassium voltage-gated channel, shaker-related subfamily, member 1(episodic ataxia with myokymia)
Protein Name: Potassium voltage-gated channel subfamily A member 1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel(465-481aa IAHYRQVNIRTANCTTA), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids .

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for KCNA1

Target: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Alternative Name: KCNA1 (KCNA1 Products)

Synonyms: AEMK antibody, EA1 antibody, HBK1 antibody, HUK1 antibody, KV1.1 antibody, MBK1 antibody, MK1 antibody, RBK1 antibody, KCNA1 antibody, AI840627 antibody, Kca1-1 antibody, Kv1.1 antibody, Mk-1 antibody, Shak antibody, mceph antibody, Kcna antibody, Kcpvd antibody, potassium voltage-gated channel subfamily A member 1 antibody, potassium voltage-gated channel, shaker-related subfamily, member 1 antibody, fragile site, aphidicolin type, common, fra(12)(q24) antibody, KCNA1 antibody, Kcna1 antibody, FRA12E antibody

Background: Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.

Synonyms: AEMK antibody|EA1 antibody|Episodic ataxia with myokymia antibody|HBK1 antibody|HUK1 antibody|Kca1 1 antibody|Kcna1 antibody|KCNA1_HUMAN antibody|Kcpvd antibody|KV1.1 antibody|MBK1 antibody|mceph antibody|MGC124402 antibody|MGC126782 antibody|MGC138385 antibody|MK1 antibody|Potassium channel protein 1 antibody|Potassium voltage gated channel shaker related subfamily member 1 antibody|Potassium voltage gated channel subfamily A member 1 antibody|Potassium voltage gated channel, shaker related subfamily, member 1(episodic ataxia with myokymia) antibody|Potassium voltage-gated channel subfamily A member 1 antibody|RBK1 antibody|Shak antibody|Shaker related subfamily member 1 antibody|Voltage gated potassium channel subunit Kv1.1 antibody|Voltage-gated K(+) channel HuKI antibody|Voltage-gated potassium channel HBK1 antibody|Voltage-gated potassium channel subunit Kv1.1 antibody

UniProt: Q09470