ERK2 antibody (Mitogen-Activated Protein Kinase 1) (AA 348-360)

Details for Product anti-MAPK1 Antibody No. ABIN3042634, Supplier: Log in to see
Antigen
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • ATMPK2
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • T30E16.13
  • T30E16_13
  • mitogen-activated protein kinase homolog 2
  • ERK2
  • zERK2
  • MAPK1
  • ERK
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • erk
  • erk2
  • ert1
  • mapk
  • mpk1
  • xp42
  • mapk2
  • prkm1
  • prkm2
  • Xp42
  • mapk1b
  • mapk1
  • mapk1a
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 2
  • mitogen activated protein kinase 1
  • ATMPK1
  • MPK1
  • MPK2
  • MAPK1
  • mapk1
  • Mapk1
  • PfMAP1
  • PVX_084965
  • Tsp_01601
  • mapk1-b
  • mapk1-a
Alternatives
anti-Human ERK2 antibody for Western Blotting
Epitope
AA 348-360, C-Term
60
21
16
11
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8
5
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4
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2
2
2
2
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2
1
1
1
1
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1
Reactivity
Human, Rat (Rattus)
355
149
119
50
31
19
14
11
10
9
8
7
5
5
2
2
2
2
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Host
Rabbit
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17
8
3
Clonality
Polyclonal
Conjugate
This ERK2 antibody is un-conjugated
10
9
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4
4
4
4
3
3
3
3
3
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3
3
3
3
2
2
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1
Application
Western Blotting (WB)
329
157
97
84
82
63
52
26
22
10
5
3
3
2
2
1
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Purpose Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 1(MAPK1) detection. Tested with WB in Human,Mouse,Rat.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human ERK2(348-360aa FEETARFQPGYRS), identical to the related rat and mouse sequences.
Sequence FEETARFQPG YRS
Isotype IgG
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 1(MAPK1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: mitogen-activated protein kinase 1
Protein Name: Mitogen-activated protein kinase 1(MAP kinase 1/MAPK 1)
Purification Immunogen affinity purified.
Alternative Name MAPK1 (MAPK1 Antibody Abstract)
Background Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme which in humans is encoded by the MAPK1 gene. The gene is mapped to 22q11.2. And The protein encoded by this gene is a member of the MAP kinase family. The deduced 360-amino acid human ERK2 protein shares 98 % identity with rat Erk2. The MAP kinase ERK2 is widely involved in eukaryotic signal transduction. Upon activation, it translocates to the nucleus of the stimulated cell, where it phosphorylates nuclear targets. Futhermore, the ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex. And the MAPK pathway is also involved in responses to NTN1.

Synonyms: ERK 2 antibody|ERK antibody|ERK-2 antibody|ERT 1 antibody|ERT1 antibody|Extracellular Signal Regulated Kinase 2 antibody|Extracellular signal-regulated kinase 2 antibody|MAP kinase 1 antibody|MAP kinase 2 antibody|MAP kinase 2 antibody|MAP kinase isoform p42 antibody|MAPK 1 antibody|MAPK 2 antibody|MAPK 2 antibody|MAPK1 antibody|MAPK2 antibody|Mitogen Activated Protein Kinase 1 antibody|Mitogen Activated Protein Kinase 2 antibody|Mitogen-activated protein kinase 1 antibody|Mitogen-activated protein kinase 2 antibody|MK01_HUMAN antibody|P38 antibody|P40 antibody|P41 antibody|P41MAPK antibody|p42 MAPK antibody|p42-MAPK antibody|P42MAPK antibody|P42MAPK antibody|PRKM 1 antibody|PRKM 2 antibody|PRKM1 antibody|PRKM2 antibody|Protein Tyrosine Kinase ERK2 antibody
UniProt P28482
Pathways MAPK Signaling, RTK Signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 348-360), (C-Term) antibody (ABIN3042634) Lane 8: COLO320 Cell Lysate
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 348-360), (C-Term) antibody (ABIN3042634) anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 348-360), (C-Term) antibody (Image 2)
Product cited in: Li, Chen, Zhang, Chen, Nie, Xu, Gong, Shen, Su, Weng, Tan, Zhao, Zeng, Zhou: "SOX9 was involved in TKIs resistance in renal cell carcinoma via Raf/MEK/ERK signaling pathway." in: International journal of clinical and experimental pathology, Vol. 8, Issue 4, pp. 3871-81, 2015 (PubMed).

Ma, Wang, Chen, Chen, Wang, Aisa: "Icariin and icaritin stimulate the proliferation of SKBr3 cells through the GPER1-mediated modulation of the EGFR-MAPK signaling pathway." in: International journal of molecular medicine, Vol. 33, Issue 6, pp. 1627-34, 2014 (PubMed).

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