RUNX3 antibody (Middle Region)

Catalog No. ABIN3042652

Product Details anti-RUNX3 Antibody

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Binding Specificity: AA 186-205, Middle Region

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Runt-related transcription factor 3(RUNX3) detection. Tested with WB in Mouse,Rat.

Sequence: QKIEDQTKAF PDRFGDLRMR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Runt-related transcription factor 3(RUNX3) detection. Tested with WB in Mouse,Rat.
Gene Name: runt-related transcription factor 3
Protein Name: Runt-related transcription factor 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse RUNX3(186-205aa QKIEDQTKAFPDRFGDLRMR), identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, The detection limit for RUNX3 is approximately 10 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3 (RUNX3 Products)

Synonyms: runxb antibody, RUNX3 antibody, CBFA3 antibody, frrunx3 antibody, runx3 antibody, aml2 antibody, cbfa3 antibody, pebp2ac antibody, AML2 antibody, Cbfa3 antibody, Pebp2a3 antibody, PEBP2aC antibody, runt-related transcription factor 3 antibody, runt related transcription factor 3 antibody, runt related transcription factor 3 L homeolog antibody, runx3 antibody, RUNX3 antibody, runx3.L antibody, Runx3 antibody

Background: Runt-related transcription factor 3, also called AML2 is a protein that in humans is encoded by the RUNX3 gene. The RUNX3 gene encodes a Runt-related transcription factor, which is part of the RUNX gene family. By fluorescence in situ hybridization, RUNX3 was assigned to human chromosome 1p36.11. RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. It may be involved in the control of cellular proliferation and/or differentiation.

Synonyms: Acute myeloid leukemia 2 protein antibody|Acute myeloid leukemia gene 2 antibody|AML 2 antibody|AML2 antibody|CBF alpha 3 antibody|CBF-alpha-3 antibody|CBFA 3 antibody|CBFA3 antibody|Core binding factor alpha 3 subunit antibody|core binding factor antibody|Core binding factor runt domain alpha subunit 3 antibody|Core binding factor subunit alpha 3 antibody|core-binding factor antibody|Core-binding factor subunit alpha-3 antibody|FLJ34510 antibody|MGC16070 antibody|Oncogene AML 2 antibody|Oncogene AML-2 antibody|PEA2 alpha C antibody|PEA2-alpha C antibody|PEBP2 alpha C antibody|PEBP2-alpha C antibody|Pebp2a3 antibody|PEBP2aC antibody|Polyomavirus enhancer binding protein 2 alpha C subunit antibody|Polyomavirus enhancer-binding protein 2 alpha C subunit antibody|runt domain alpha subunit 3 antibody|runt related transcription factor 3 antibody|Runt-related transcription factor 3 antibody|RUNX 3 antibody|Runx3 antibody|RUNX3_HUMAN antibody|SL3 3 enhancer factor 1 alpha C subunit antibody|SL3-3 enhancer factor 1 alpha C subunit antibody|SL3/AKV core binding factor alpha C subunit antibody|SL3/AKV core-binding factor alpha C subunit antibody|Transcription factor AML2 antibody

UniProt: Q64131