SLC22A5 antibody (C-Term)

Catalog No. ABIN3042852

Product Details anti-SLC22A5 Antibody

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Binding Specificity: AA 531-547, C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Solute carrier family 22 member 5(SLC22A5) detection. Tested with WB in Mouse,Rat.

Sequence: KQWQIQSQTR MQKDGEE

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Solute carrier family 22 member 5(SLC22A5) detection. Tested with WB in Mouse,Rat.
Gene Name: solute carrier family 22(organic cation/carnitine transporter), member 5
Protein Name: Solute carrier family 22 member 5

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Solute carrier family 22 member 5(531-547aa KQWQIQSQTRMQKDGEE), different from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC22A5

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Alternative Name: SLC22A5 (SLC22A5 Products)

Synonyms: CDSP antibody, OCTN2 antibody, OCTN2VT antibody, Lstpl antibody, Octn2 antibody, jvs antibody, slc22a5 antibody, MGC68932 antibody, CT1 antibody, UST2r antibody, ATOCT2 antibody, OCT2 antibody, ORGANIC CATION TRANSPORTER 2 antibody, YUP8H12R.2 antibody, YUP8H12R_2 antibody, organic cation/carnitine transporter 2 antibody, solute carrier family 22 member 5 antibody, solute carrier family 22 (organic cation transporter), member 5 antibody, solute carrier family 22 member 5 L homeolog antibody, organic cation/carnitine transporter 2 antibody, SLC22A5 antibody, Slc22a5 antibody, LOC100358417 antibody, slc22a5.L antibody, OCT2 antibody

Background: Solute carrier family 22(organic cation/carnitine transporter), member 5, also called SLC22A5 or OCTN2 is a membrane transport protein associated with primary carnitine deficiency. This gene is mapped to 5q31.1. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency(CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Synonyms: CDSP antibody|High-affinity sodium-dependent carnitine cotransporter antibody|OCTN2 antibody|OCTN2VT antibody|Organic cation/carnitine transporter 2 antibody|S22A5_HUMAN antibody|Slc22a5 antibody|Solute carrier family 22(organic cation/carnitine transporter) member 5 antibody|Solute carrier family 22 member 5 antibody

UniProt: Q9Z0E8