SLC22A1 antibody (C-Term)

Catalog No. ABIN3042854

Product Details anti-SLC22A1 Antibody

Target: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Binding Specificity: AA 533-550, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Solute carrier family 22 member 1(SLC22A1) detection. Tested with WB in Human.

Sequence: RKAKPKENTI YLKVQTSE

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Solute carrier family 22 member 1(SLC22A1) detection. Tested with WB in Human.
Gene Name: solute carrier family 22(organic cation transporter), member 1
Protein Name: Solute carrier family 22 member 1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC22A1(533-550aa RKAKPKENTIYLKVQTSE), different from the related mouse and rat sequences by six amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC22A1

Target: SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))

Alternative Name: SLC22A1 (SLC22A1 Products)

Synonyms: SLC22A1 antibody, OCT1 antibody, HOCT1 antibody, oct1_cds antibody, Lx1 antibody, Oct1 antibody, Orct antibody, Orct1 antibody, Roct1 antibody, SLC22A2 antibody, solute carrier family 22 member 1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, solute carrier family 22 member 2-like antibody, SLC22A1 antibody, Slc22a1 antibody, LOC421584 antibody

Background: Solute carrier family 22(organic cation transporter), member 1, also called SLC22A1 or OCT1 is a protein that in humans is encoded by the SLC22A1 gene. This gene is mapped to 6q25.3. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene transports the polyamines spermine and spermidine. It also transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. This gene regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.

Synonyms: hOCT1 antibody|OCT1 antibody|oct1_cds antibody|Organic cation transporter 1 antibody|S22A1_HUMAN antibody|Slc22a1 antibody|solute carrier family 22(organic cation transporter), member 1 antibody|Solute carrier family 22 member 1 antibody

UniProt: O15245

Pathways: Hormone Transport