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SDC3 antibody (N-Term)

SDC3 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042886
  • Target See all SDC3 Antibodies
    SDC3 (Syndecan 3 (SDC3))
    Binding Specificity
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 45-60, N-Term
    Reactivity
    • 50
    • 15
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat
    Host
    • 48
    • 2
    Rabbit
    Clonality
    • 47
    • 3
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SDC3 antibody is un-conjugated
    Application
    • 39
    • 18
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Syndecan-3(SDC3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    AQRWRNENFE RPVDLE
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Syndecan-3(SDC3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: syndecan 3
    Protein Name: Syndecan-3
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of mouse Syndecan 3/SDC3 (45-60aa AQRWRNENFERPVDLE), identical to the related rat sequence, and different from the related human sequence by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product SDC3 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Yao, Zhang, Huang, Li, Gao: "Pleiotrophin and N-syndecan promote perineural invasion and tumor progression in an orthotopic mouse model of pancreatic cancer." in: World journal of gastroenterology, Vol. 23, Issue 21, pp. 3907-3914, (2017) (PubMed).

    Yao, Li, Li, Feng, Gao: "Midkine promotes perineural invasion in human pancreatic cancer." in: World journal of gastroenterology, Vol. 20, Issue 11, pp. 3018-24, (2014) (PubMed).

  • Target
    SDC3 (Syndecan 3 (SDC3))
    Alternative Name
    SDC3 (SDC3 Products)
    Synonyms
    wu:fa97a01 antibody, SDC3 antibody, sdcn antibody, synd3 antibody, Xsyn-3 antibody, N-syndecan antibody, SDCN antibody, SYND3 antibody, Synd3 antibody, mKIAA0468 antibody, syn-3 antibody, syndecan 3 antibody, sdc3 antibody, SDC3 antibody, Sdc3 antibody
    Background
    Syndecan-3, also called SYND3 is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.

    Synonyms: N-syndecan antibody|Sdc3 antibody|SDC3_HUMAN antibody|SDCN antibody|SYND3 antibody|syndecan proteoglycan 3 antibody|Syndecan-3 antibody
    UniProt
    Q64519
    Pathways
    Glycosaminoglycan Metabolic Process
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