Digoxin (DIG) antibody
| Catalog no. |
ABIN304291 |
| Quantity |
1000 µg |
| Price |
446.67 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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Digoxin
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Immunogen
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Digoxin conjugated to bovine serum albumin.
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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26G10 (DIGO-001)
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Description
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Gene: Digoxin
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Specificity
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Specific for digoxin and Reacts with Digitoxin. Digoxin is a glycoside extracted from the foxglove plant Digitalis lanata. Its primary mechanism of action is to inhibit alpha subunits of the Na+/K+ ATPase pump located in the plasma membrane of human myocytes. This inhibition leads to an increase in intracellular calcium concentration and an increase in myocardial contraction. Digoxin also results in a decrease of electrical impulse conduction through the AV node. Digoxin is widely used in the treatment of various heart conditions, namely atrial fibrillation, atrial flutter and atrial tachycardia
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Application Notes
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ELISA, RIA
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Purification
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DEAE-column Chromatography
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Buffer
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PBS, pH 7.2, 0.09% sodium azide.
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Storage
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Long term: -20°C, Short term: -20°C
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Research Area
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Cardiovascular, Contractility, Drugs
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Restrictions
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For Research Use only
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Alternatives for antigen "Digoxin (DIG)", type "Antibodies"
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Hosts
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Mouse (41), Rabbit (23), Goat (8), Sheep (6), Chicken (1)
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Reactivities
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Compound (14), Human (10), Mouse (Murine) (10), Rat (Rattus) (10), Cow (Bovine) (5), Pig (Porcine) (5), Dog (Canine) (4), Chicken (2), Rabbit (2), Fruit Fly (Drosophila melanogaster) (1), Guinea Pig (1), Horse (Equine) (1), Sheep (Ovine) (1), Zebrafish (Brachydanio rerio) (1)
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Applications
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ELISA (24), Radioimmunoassay (RIA) (24), Flow Cytometry (FACS) (23), Immunofluorescence (IF) (23), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Western Blotting (WB) (2), Immunoelectron Microscopy (IEM) (1), To be determined by user (TBD) (1)
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Conjugates
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Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
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