ANGPTL3 antibody (N-Term)

Catalog No. ABIN3042916

Product Details anti-ANGPTL3 Antibody

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Binding Specificity: AA 32-48, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Angiopoietin-related protein 3(ANGPTL3) detection. Tested with WB in Human,Mouse,Rat.

Sequence: EPKSRFAMLD DVKILAN

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Angiopoietin-related protein 3(ANGPTL3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: angiopoietin-like 3
Protein Name: Angiopoietin-related protein 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ANGPTL3(32-48aa EPKSRFAMLDDVKILAN), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for ANGPTL3 is approximately 1.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Alternative Name: ANGPTL3 (ANGPTL3 Products)

Synonyms: fb60e11 antibody, fb66h02 antibody, wu:fb60e11 antibody, wu:fb66h02 antibody, zgc:111943 antibody, ANGPTL3 antibody, LOC100230785 antibody, ANG-5 antibody, ANGPT5 antibody, ANL3 antibody, FHBL2 antibody, hypl antibody, angiopoietin-like 3 antibody, angiopoietin like 3 antibody, angptl3 antibody, ANGPTL3 antibody, Angptl3 antibody

Background: ANGPTL3(Angiopoietin-Like 3), also known as ANGPT5, is a protein which in humans is encoded by the ANGPTL3 gene. The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. By radiation hybrid mapping and the use of surrounding genes, Conklin et al.(1999) mapped the ANGPTL3 gene to chromosome 1p31. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen(FBN)-like domain. Angptl3 also acts as dual inhibitor of lipoprotein lipase(LPL) and endothelial lipase(EL), and increases plasma triglyceride and HDL cholesterol in rodents. ANGPTL3 inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels.

Synonyms: ANG 5 antibody|ANG-5 antibody|ANG5 antibody|Angiopoietin 5 antibody|Angiopoietin like 3 antibody|Angiopoietin related protein 3 antibody|Angiopoietin-5 antibody|Angiopoietin-like protein 3 antibody|Angiopoietin-related protein 3 antibody|ANGL3_HUMAN antibody|ANGPT5 antibody|ANGPTL3 antibody|ANL3 antibody|FHBL2 antibody|OTTHUMP00000010719 antibody|UNQ153/PRO179 antibody

UniProt: Q9Y5C1