CXCR5 antibody (C-Term)

Catalog No. ABIN3042947

Product Details anti-CXCR5 Antibody

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Binding Specificity: AA 358-372, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 5(CXCR5) detection. Tested with WB in Human,Mouse,Rat.

Sequence: SSLSESENAT SLTTF

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 5(CXCR5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: chemokine(C-X-C motif) receptor 5
Protein Name: C-X-C chemokine receptor type 5

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CXCR5(358-372aa SSLSESENATSLTTF), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: CXCR5 (CXCR5 Products)

Synonyms: BLR1 antibody, CRL1 antibody, CD185 antibody, MDR15 antibody, Blr1 antibody, CXC-R5 antibody, CXCR-5 antibody, Gpcr6 antibody, NLR antibody, C-X-C motif chemokine receptor 5 antibody, chemokine (C-X-C motif) receptor 5 antibody, CXCR5 antibody, Cxcr5 antibody

Background: CXCR5(Chemokine CXC Motif Receptor 5), also known as BLR1, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13(also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).

Synonyms: BLR 1 antibody|BLR1 antibody|Burkitt lymphoma receptor 1 antibody|Burkitt lymphoma receptor 1 GTP binding protein antibody|C X C chemokine receptor type 5 antibody|C-X-C chemokine receptor type 5 antibody|CD 185 antibody|CD185 antibody|CD185 antigen antibody|Chemokine C X C motif receptor 5 antibody|Chemokine CXC motif receptor 5 antibody|Chemokine receptor 5 antibody|CXC chemokine receptor type 5 antibody|CXC R5 antibody|CXC-R5 antibody|CXCR 5 antibody|CXCR-5 antibody|Cxcr5 antibody|CXCR5_HUMAN antibody|MDR 15 antibody|MDR-15 antibody|MDR15 antibody|MGC117347 antibody|Monocyte derived receptor 15 antibody|Monocyte-derived receptor 15 antibody

UniProt: P32302