Apelin antibody (C-Term)

Catalog No. ABIN3043182

Product Details anti-Apelin Antibody

Target: Apelin (APLN)

Binding Specificity: AA 60-77, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apelin antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Apelin(APLN) detection. Tested with WB in Human,Mouse,Rat.

Sequence: RKFRRQRPRL SHKGPMPF

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Apelin(APLN) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: apelin
Protein Name: Apelin

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apelin(60-77aa RKFRRQRPRLSHKGPMPF), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Apelin

Target: Apelin (APLN)

Alternative Name: APLN (APLN Products)

Synonyms: APLN antibody, Xapelin antibody, xnpep2 antibody, preproapelin antibody, 6030430G11Rik antibody, Apel antibody, APEL antibody, XNPEP2 antibody, apelin antibody, apelin S homeolog antibody, apln antibody, APLN antibody, apln.S antibody, Apln antibody

Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Synonyms: AGTRL1 ligand antibody|APEL antibody|APEL_HUMAN antibody|Apelin-13 antibody|APJ endogenous ligand antibody|Apln antibody|XNPEP2 antibody

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour